Figure 5.
Protein concentrations in the EV fractions of static and dynamic conditions MPC cultures as measured by Luminex. N = 3 for all conditions. All samples were concentrated at a factor of 40×, the volume of the medium from which they were isolated (∗P < .05, ∗∗∗P < .001, ∗∗∗∗P < .0001 relative to static controls). Abbreviations: EV, extracellular vesicle; FGF-2, basic fibroblast growth factor 2; HGF, hepatocyte growth factor; MMP, matrix metalloproteinase; MPC, mesenchymal progenitor cell; TIMP, tissue inhibitor of metalloproteinase; VEGF-A, vascular endothelial growth factor A.