Table 3.
RDT accuracy for detecting pLDH and HRP2 antigens compared to bead-based assay
pLDH RDT band | HRP2 RDT band | ||
---|---|---|---|
Sensitivity |
% (95% CI) n/N |
53.8 (25.1–80.8) 7/13 |
53.3 (34.3–71.7) 16/30 |
Specificity |
% (95% CI) n/N |
99.6 (99.3–99.8) 2624/2635 |
99.7 (99.3–99.8) 2609/2618 |
PPV | % (95% CI) | 38.9 (17.3–64.3) | 64.0 (42.5–82.0) |
NPV | % (95% CI) | 99.8 (99.5–99.9) | 99.5 (99.1–99.7) |
Kappa coefficient | % (95% CI) | 0.45 (0.23–0.67) | 0.58 (0.42–0.73) |
CI: Confidence interval; PPV: Positive predictive value; NPV: Negative predictive value