Figure 6.
TLR2 knockout attenuated surgery-induced learning and memory dysfunction in mice. C57BL/6J mice and TLR2−/− mice were subjected to Barnes maze and fear conditioning tests from 1 week after surgery. (a) Training sessions of Barnes maze test. (b) Memory phase of Barnes maze test. (c) Fear conditioning tests. Results in panel a are means ± S.E.M. (n = 7, the n number referred to the number of animals). Results in other panels are in box plot format (n = 7, the n number referred to the number of animals). ● : lowest or highest score (the score will not show up if it falls in the 95th percentile); between lines: 95th percentile of the data; inside boxes: 25th to 75th percentile including the median of the data. * P < 0.05 compared with the corresponding data on day 1. ^ P < 0.05 compared with control.