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. 2022 Mar 4;20:108. doi: 10.1186/s12967-022-03309-7

Table 5.

Participants’ characteristics of the GKASC grouped by HTN stage

Variables Overall Normal Pre-HTN  ≥ Stage 1 HTN P value
N = 1881 n = 485 (25.78%) n = 938 (49.87%) n = 458 (24.35%)
Age (years) 65.00 (62.00–70.00) 65.00 (62.00–69.00) 65.00 (62.00–69.00) 66.00 (63.00–72.00)  < 0.001
Male (n, %) 823 (43.75) 200 (41.24) 423 (45.10) 200 (43.67) 0.380
WC (cm) 81.00 (75.00–88.00) 80.00 (74.00–87.00) 80.00 (75.00–87.00) 82.00 (76.00–89.00)  < 0.001
BMI (kg/m2) 22.23 (20.45–24.46) 22.06 (20.17–24.12) 22.23 (20.36–24.46) 22.54 (20.85–24.77) 0.006
Leukocyte (× 109/L) 5.90 (5.10–7.00) 5.80 (4.80–6.92) 5.90 (5.10–7.10) 6.00 (5.30–7.00) 0.095
Platelet (× 109/L) 217.00 (190.00–252.00) 217.00 (188.00–251.50) 217.00 (189.00–250.00) 220.00 (193.00–254.00) 0.409
Hemoglobin (g/L) 135.00 (126.00–144.00) 134.00 (126.00–143.00) 135.00 (127.00–144.00) 135.00 (126.00–145.00) 0.324
FPG (mmol/L) 4.99 (4.50–5.60) 5.00 (4.40–5.55) 4.93 (4.50–5.60) 4.98 (4.50–5.60) 0.617
ALT (U/L) 20.95 (16.33–27.50) 20.40 (15.70–25.45) 20.70 (16.50–27.50) 22.80 (17.10–30.20)  < 0.001
AST (U/L) 21.00 (18.00–24.20) 20.00 (18.00–23.90) 21.00 (18.00–24.00) 21.00 (18.00–26.00) 0.006
Albumin (g/L) 44.60 (42.90–46.00) 44.20 (42.75–45.50) 44.60 (42.80–46.10) 44.75 (43.20–46.30) 0.017
STB (μmol/L) 11.90 (9.25–15.20) 12.00 (9.10–15.10) 11.90 (9.28 -15.23) 11.85 (9.40–15.40) 0.723
CB (μmol/L) 3.20 (2.20–4.40) 3.00 (2.10–4.10) 3.10 (2.10–4.50) 3.30 (2.38–4.60) 0.053
UCB (μmol/L) 8.30 (5.90–11.45) 8.60 (5.95–11.60) 8.30 (5.70–11.50) 8.10 (6.10–11.13) 0.782
SCr (μmol/L) 62.80 (51.70–75.80) 62.70 (50.70–76.35) 63.10 (51.98–75.50) 62.60 (52.25–76.13) 0.853
TC (mmol/L) 5.03 (4.40–5.71) 5.06 (4.42–5.69) 5.05 (4.42–5.79) 5.00 (4.32–5.64) 0.107
TG (mmol/L) 1.04 (0.77–1.48) 1.00 (0.74–1.38) 1.05 (0.77–1.52) 1.07 (0.81–1.55) 0.050
T2DM (n, %) 176 (9.36) 39 (8.04) 93 (9.91) 44 (9.61)
Hyperuricemia (n, %) 468 (24.88) 124 (25.57) 216 (23.05) 128 (27.95)
Marriage Status (n, %) 0.486
 Married 1649 (87.67) 432 (89.07) 818 (87.21) 399 (87.12)
 Widowed 220 (11.70) 50 (10.31) 116 (12.37) 54 (11.79)
 Unspecified 12 (0.64) 3 (0.62) 4 (0.43) 5 (0.11)
Smoking Habits 0.958
 Non-smoker 1395 (74.16) 365 (75.26) 689 (73.45) 341 (74.45)
 Former Smoker 59 (3.14) 14 (0.29) 30 (3.20) 15 (3.28)
 Current Smoker 427 (22.70) 106 (21.86) 219 (23.35) 102 (22.27)
Drinking Habits 0.375
 Non-drinker 831 (87.81) 425 (87.81) 800 (85.29) 390 (85.15)
 Current Drinker 121 (12.70) 59 (12.19) 138 (14.71) 68 (14.85)
Exercise frequency 0.880
 Low 1109 (58.96) 294 (60.62) 552 (58.85) 263 (57.42)
 Medium 171 (9.09) 41 (8.45) 88 (9.38) 42 (9.17)
 High 601 (31.95) 150 (30.93) 298 (31.77) 153 (33.41)

Normally distributed variables with even variance were presented as mean ± SD, skewed variables as median (interquartile range), and categorical variables as n (%)

Continuous variables were compared using Student’s t-test or Mann–Whitney U test depending on distribution. Pearson’s χ2 tests were used to compare categorical values

HTN, hypertension; WC, waist circumference; BMI, body mass index; FPG, fasting plasm blood; ALT, alanine aminotransferase; AST, aspartate aminotransferase; STB, serum total bilirubin; CB, conjugated bilirubin; UCB, unconjugated bilirubin; SCr, serum creatinine; TC, total cholesterol; TG, triglyceride; T2DM, type 2 diabetes mellitus