Table 1.

Imaging Protocol in Suspected Cases of Mucormycosis

ROCM-Imaging Techniques
CT of the brain, orbits, and PNS	MRI of the brain, orbits, and PNS
• Vertex to mandible with contrast	• Axial FLAIR, DWI, SWI of brain
• Assessment of	• T1WI and T2WI orbit/PNS in at least 2 planes (3-mm fat-suppressed)
- Sinus contents	• Postcontrast T1WI 3D axial brain
- Bone erosion or osteomyelitis	• Postcontrast FS T1WI orbit/PNS
- Perisinus or orbital invasion	• Superior for assessment of soft tissue, perineural, vascular, and brain invasion
- Brain lesions (infarct, vasogenic edema, hemorrhage or abscess)	• Scan duration ∼25 minutes.
• CT angiogram—If thrombus or pseudoaneurysm (mycotic) is suspected
• CT may under stage extent of disease

ROCM, rhino-orbital-cerebral mucormycosis; CT, computed tomography; PNS, paranasal sinuses; MRI, magnetic resonance imaging; FLAIR, fluid-attenuated inversion recovery; DWI, diffusion-weighted imaging; SWI, susceptibility-weighted imaging; WI, weighted imaging; 3D, 3-dimensional; FS, fat-suppressed.