Table 2.
Significant risk factors for all-cause mortality and CV events.
| Risk factors | Univariable logistic regression |
Multivariable logistic regression |
||
|---|---|---|---|---|
| HR (95%CI) | p Value | HR (95%CI) | p Value | |
| All-cause mortality | ||||
| C2 vs C1 | 0.43 (0.31–0.62) | <.001 | 0.86 (0.79–0.94) | .001 |
| Sex ( female vs male) | 2.13 (1.51–3.03) | <.001 | 2.20 (1.45–3.33) | <.001 |
| Age (years) | 1.09 (1.07–1.10) | <.001 | 1.06 (1.04–1.08) | <.001 |
| Diabetes (yes vs no) | 6.21 (4.29–8.98) | <.001 | 2.69 (1.70–4.25) | <.001 |
| Hypertension (yes vs no) | 5.20 (3.35–8.07) | <.001 | 2.03 (1.20–3.45) | .009 |
| CVD history (yes vs no) | 5.81 (3.99–8.45) | <.001 | 2.23 (1.41–3.54) | .001 |
| β-blocker (yes vs no) | 1.42 (1.01–2.02) | .047 | 1.78 (1.17–2.71) | .007 |
| Aspirin (yes vs no) | 5.85 (3.73–9.18) | <.001 | ||
| DBP (mm Hg) | 0.96 (0.94–0.97) | <.001 | ||
| Creatinine (umol/L) | 0.998 (0.998–0.999) | <.001 | ||
| Urea nitrogen (mmol/L) | 0.95 (0.93–0.97) | <.001 | ||
| FBG (mmol/L) | 1.23 (1.15–1.31) | <.001 | ||
| Cholesterol (mmol/L) | 1.31 (1.13–1.51) | <.001 | ||
| Potassium (mmol/L) | 0.60 (0.46–0.76) | <.001 | ||
| ACEI/ARB (yes vs no) | 1.57 (1.11–2.24) | .012 | ||
| Calcium (mmol/L) | 2.00 (1.04–3.97) | .047 | ||
| Uric acid (mmol/L) | 0.998 (0.996–1.00) | .028 | ||
| Phosphorus (mmol/L) | 0.72 (0.53–0.97) | .032 | ||
| RRF (mL/min) | 0.99 (0.98–1.00) | .047 | ||
| CV events | ||||
| Age (years) | 1.06 (1.04–1.08) | <.001 | 1.04 (1.02–1.06) | <.001 |
| Hypertension (yes vs no) | 5.44 (3.09–9.60) | <.001 | 3.49 (1.89–6.45) | <.001 |
| Aspirin (yes vs no) | 5.46 (3.35–8.89) | <.001 | 2.20 (1.23–3.92) | .008 |
| SBP (mm Hg) | 0.99 (0.98–1.00) | .029 | 0.99 (0.98–1.00) | .037 |
| FBG (mmol/L) | 1.21 (1.13–1.30) | <.001 | 1.13 (1.04–1.22) | .003 |
| β-blocker (yes vs no) | 1.63 (1.07–2.50) | .024 | 2.02 (1.26–3.24) | .004 |
| DBP (mm Hg) | 0.96 (0.94–0.98) | <.001 | ||
| C2 vs C1 | 0.50 (0.33–0.76) | .001 | ||
| ACEI/ARB (yes vs no) | 1.97 (1.27–3.06) | .002 | ||
| CVD history (yes vs no) | 3.33 (2.16–5.14) | <.001 | ||
| Diabetes (yes vs no) | 3.52 (2.30–5.38) | <.001 | ||
PPI: proton pump inhibitor; C1: center 1; C2: center 2; CVD: cardiovascular disease; BP: blood pressure; FBG: fasting blood glucose; ACEI: angiotensin converting enzyme inhibitors; ARB: angiotensin receptor blocker; RRF: residual renal function.