Table 2.

Key Transcription Regulated Factors of the Differentially Expressed CXC Chemokines in LUAD

Key TF	Regulated Gene	P-value	FDR
RELA	CXCL1, CXCL2, CXCL5, CXCL10, CXCL12	1.16e-06	1.79e-06
NFκB1	CXCL1, CXCL2, CXCL5, CXCL10, CXCL12	1.19e-16	1.79e-06
Sp1	CXCL1, CXCL5, CXCL14	0.00369	0.00369

Abbreviations: CXC, cysteine-X (any amino acid)-cysteine motif; LUAD, lung adenocarcinoma; TF, transcription factor; RELA, v-relreticuloendotheliosis viral oncogene homolog avian; NFκB1, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; SP1, Sp1 transcription factor; FDR, false discovery rate.