Table 4.
Multivariate Cox Proportional Hazard Model of CXC Chemokines and 6 Infiltrating Immune Cells in LUAD
| Variables | Coef | HR | 95% CI_l | 95% CI_u | P-value |
|---|---|---|---|---|---|
| B cell | −4.482 | 0.011 | 0.001 | 0.176 | 0.001 |
| CD8+T cell | 0.104 | 1.109 | 0.131 | 9.356 | 0.924 |
| CD4+T cell | 2.363 | 10.624 | 0.479 | 235.690 | 0.135 |
| Macrophage | 0.072 | 1.075 | 0.070 | 16.577 | 0.959 |
| Neutrophil | −1.923 | 0.0146 | 0.001 | 19.080 | 0.439 |
| Dendritic | 0.224 | 1.251 | 0.288 | 5.440 | 0.765 |
| CXCL1 | −0.031 | 0.969 | 0.824 | 1.140 | 0.707 |
| CXCL2 | −0.078 | 0.925 | 0.785 | 1.090 | 0.353 |
| CXCL3 | 0.217 | 1.243 | 0.981 | 1.574 | 0.071 |
| CXCL5 | 0.036 | 1.037 | 0.941 | 1.143 | 0.465 |
| CXCL6 | 0.010 | 1.010 | 0.877 | 1.164 | 0.887 |
| CXCL9 | −0.006 | 0.994 | 0.798 | 1.239 | 0.958 |
| CXCL10 | −0.116 | 0.890 | 0.635 | 1.249 | 0.501 |
| CXCL11 | 0.195 | 1.215 | 0.927 | 1.594 | 0.159 |
| CXCL12 | −0.030 | 0.970 | 0.830 | 1.134 | 0.702 |
| CXCL13 | −0.017 | 0.984 | 0.879 | 1.100 | 0.771 |
| CXCL14 | 0.045 | 1.046 | 0.978 | 1.119 | 0.193 |
| CXCL16 | −0.081 | 0.923 | 0.747 | 1.139 | 0.454 |
| CXCL17 | −0.072 | 0.931 | 0.857 | 1.011 | 0.087 |
Abbreviations: CXC, cysteine-X (any amino acid)-cysteine motif; LUAD, lung adenocarcinoma; coef, regression coefficient; HR, hazard ratio; 95% CI_l and 95%Cl_u, lower and upper 95% confidential interval.