Table 5.
Association between 30-day mortality and hypertension subclassified into six blood pressure stages according to JNC8 criteria in COVID-19 patients adjusted for confounders, multivariable logistic regression (n = 9,531).
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|---|---|---|---|---|---|---|
| AVAILABLE DATA IN THE UNIVARIABLE ANALYSIS N = 9,531 | PATIENTS WHO DIED N = 112 | UNIVARIABLE | MULTIVARIABLE | |||
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| CRUDE ODDS RATIO (95% CI) | P VALUE | ADJUSTED ODDS RATIO (95% CI) | P VALUE | |||
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| Arterial Hypertension | ||||||
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| Normal | 6,697 | 13 (0.2) | 1 (ref) | 1 (ref) | .. | |
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| Elevated | 568 | 8 (1.4) | 7.35 (3.03–17.79) | <0.001 | 2.49 (0.94–6.64) | 0.068 |
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| Stage-1 untreated | 457 | 0 | 0 | 0.994 | 0 | 0.992 |
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| Stage-1 treated | 711 | 18 (2.5) | 13.35 (6.52–27.37) | <0.001 | 1.25 (0.56–2.81) | 0.590 |
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| Stage-2 untreated | 233 | 14 (6.0) | 32.87 (15.27–70.76) | <0.001 | 1.73 (0.74–4.02) | 0.203 |
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| Stage-2 treated | 865 | 59 (6.8) | 37.63 (20.55–68.92) | <0.001 | 1.49 (0.75–2.99) | 0.258 |
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| Age, years | 9,531 | 1.13 (1.11–1.15) | <0.001 | 1.09 (1.07–1.12) | < 0.001 | |
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| Sex | ||||||
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| Male | 4,689 | 48 (1.0) | 1 (ref) | 1 (ref) | .. | |
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| Female | 4,842 | 64 (1.3) | 1.29 (0.89–1.89) | 0.178 | 0.97 (0.63–1.51) | 0.909 |
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| Myocardial infarction | ||||||
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| No | 8,612 | 57 (0.7) | 1 (ref) | 1 (ref) | .. | |
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| Yes | 919 | 55 (5.9) | 18.01 (12.29–26.38) | <0.001 | 2.68 (1.67–4.31) | < 0.001 |
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| Obesity | ||||||
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| No | 7,845 | 18 (0.2) | 1 (ref) | 1 (ref) | .. | |
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| Yes | 1,686 | 94 (5.6) | 25.68 (15.46–42.63) | <0.001 | 7.18 (4.18–12.44) | < 0.001 |
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| Diabetes | ||||||
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| No | 8,509 | 31 (0.4) | 1 (ref) | 1 (ref) | .. | |
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| Yes | 1,022 | 81 (7.9) | 23.54 (15.48–35.81) | <0.001 | 4.18 (2.58–6.76) | < 0.001 |
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Data are n (%) unless otherwise specified. CI = confidence interval.