Table 3.

Cumulative incidence of local/distant metastasis by potential risk factors for patients with colorectal cancer after resection surgery

Variable	Category	Cumulative incidence (months)
		12	24	36	48
All patients		0.09	0.18	0.25	0.30
Age	< 60	0.11	0.23	0.31	0.37
	60–74	0.08	0.16	0.24	0.31
	≥ 75	0.08	0.16	0.24	0.24
Sex	Male	0.03	0.15	0.23	0.27
	Female	0.16	0.21	0.29	0.33
Tumour location	Colon	0.15	0.17	0.23	0.23
	Sigmoid/rectosigmoid	0.09	0.29	0.32	0.39
	Rectum	0.02	0.10	0.24	0.31
Tumor type	Adenocarcinoma	0.06	0.16	0.23	0.28
	Mucinous adenocarcinoma	0.32	0.32	0.48	0.48
Histological grade	Low/well differentiated	0.04	0.16	0.22	0.28
	Moderate	0.11	0.20	0.26	0.30
	High/poorly differentiated	0.07	0.07	0.29	0.29
T stage (depth)	T1/ T2	0.00	0.07	0.10	0.14
	T3	0.07	0.16	0.28	0.33
	T4	0.52	0.71	0.71	0.71
N stage (nodes)	N0	0.03	0.10	0.13	0.15
	N1	0.06	0.16	0.27	0.27
	N2	0.35	0.52	0.73	0.90
Vascular invasion	Absent	0.04	0.13	0.16	0.16
	Present/suspicious	0.22	0.28	0.51	0.64
Perineural invasion	Absent	0.07	0.14	0.22	0.25
	Present	0.13	0.28	0.37	0.44
Positive margins	Uninvolved	0.06	0.15	0.22	0.26
	One positive margin	0.36	0.43	0.58	0.69
Nodes examined	< 12	0.08	0.17	0.20	0.24
	≥ 12	0.09	0.18	0.27	0.31
Post-operative adjuvant therapy	None	0.08	0.14	0.14	0.16
	Chemotherapy or radiation	0.09	0.25	0.49	0.60