Table 4.

Correlations Between TLR3 and Infiltrating Immune Cells and Mann–Whitney U-Test Between TLR3^low and TLR3^high Groups

Characteristics	Without Adjusted		Purity Adjusted		Mann–Whitney U-test
	Correlation	P value	Correlation	P value
Activated B cell	0.407	1.655e-4***	0.294	0.008**	0.0018**
Activated CD4 T cell	0.526	4.575e-7***	0.400	2.380e-4**	9.006e-6***
Activated CD8 T cell	0.615	9.681e-10***	0.499	2.000e-6***	2.500e-7***
Activated dendritic cell	0.478	6.322e-6***	0.348	0.002**	6.982e-5***
CD56bright natural killer cell	0.227	0.042*	0.186	0.099	0.073
CD56dim natural killer cell	0.057	0.611	−0.110	0.330	0.253
Central memory CD4 T cell	0.338	0.002**	0.073	0.518	0.013*
Central memory CD8 T cell	0.032	0.777	−0.208	0.064	0.770
Effector memory CD4 T cell	0.167	0.136	−0.084	0.461	0.126
Effector memory CD8 T cell	0.613	1.192e-9***	0.504	2.000e-6***	2.116e-6***
Eosinophil	0.216	0.052	0.045	0.692	0.031*
Gamma delta T cell	0.242	0.030*	0.076	0.502	0.450
Immature B cell	0.475	7.530e-6***	0.335	0.002**	5.068e-5***
Immature dendritic cell	0.281	0.011*	0.101	0.371	0.031*
Macrophage	0.267	0.016*	0.035	0.760	0.180
Mast cell	0.213	0.056	−0.028	0.804	0.238
Memory B cell	0.073	0.518	−0.070	0.535	0.473
Monocyte	0.317	0.004**	0.145	0.200	0.004**
Natural killer cell	0.428	6.616e-5***	0.298	0.007**	0.001**
Natural killer T cell	0.485	1.216e-5***	0.330	0.003**	0.001**
Neutrophil	0.062	0.583	0.068	0.547	0.473
Plasmacytoid dendritic cell	0.267	0.016*	0.087	0.442	0.077
Regulatory T cell	0.297	0.007**	0.002	0.988	0.104
T follicular helper cell	0.459	1.631e-5***	0.266	0.017*	0.001**
Type 1 T helper cell	0.494	2.808e-6***	0.378	0.001**	1.519e-4***
Type 17 T helper cell	0.194	0.083	0.141	0.211	0.023*
Type 2 T helper cell	0.427	6.935e-5***	0.256	0.022*	1.978e-4***
Macrophages M1	0.581	1.314e-8***	0.491	3.806e-6***	3.628e-5**
Macrophages M2	−0.126	0.262	−0.276	0.013*	0.029*
MDSCs	0.456	1.915e-5***	0.279	0.012*	0.001**
CAFs	−0.110	0.932	−0.354	0.001**	0.770

Notes: *P < 0.05, **P < 0.01, ***P < 0.001.