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. 2022 Mar 4;101(9):e28992. doi: 10.1097/MD.0000000000028992

Table 2.

Comparison of the clinical outcomes from 2 high-quality embryos per transfer.

≤35 years (average age 29.92 years) 36–37 years (average age 36.44 years) ≥38 years (average age 40.36 years) P value
Embryo transfer cycles 3758 296 318
Duration of infertility (yrs) 3.4 ± 0.1 5.8 ± 0.8 7.8 ± 1.3 <.001
Embryos from ICSI 1103 (29.4%) 77 (26.0%) 116 (36.5%) .01
Endometrium thickness (mm) 9.4 ± 0.0 9.3 ± 0.1 9.1 ± 0.1 .026
Pregnancy rate per cycle 2734 (72.8%) 174 (58.8%) 143 (45.0%) <.001
Implantation rate per cycle 3831 (51.0%) 232 (39.2%) 173 (27.2%) <.001
Live birth rate per cycle 2416/3758 (64.3%) 161/296 (54.4%) 123/318 (38.7%) <.001
Multi pregnancy rate (%) 942/2416 (39.0%) 48/161 (29.8%) 24/123 (19.5%) <.001
Gestational days (d) 263.1 ± 1.1 260.5 ± 5.1 268.5 ± 1.4 .61
Neonatal weight (g) 2969.8 ± 17.8 3141.8 ± 83.3 3268.6 ± 86.5 .001
Preterm birth (<37 wks) 312/2416 (12.9%) 22/161 (13.7%) 13/123 (10.6%) .713

ICSI = intracytoplasmic sperm injection.