TABLE 1.

Summary of several commercially available treatments for wound regeneration.

Name	Type	Source	Composition	Components relevant to wound healing	References
Epicel	Autograft	Human keratinocytes	Cultured keratinocytes in a fibrin mesh	Not reported	Nathoo et al. (2014)
CellSpray	Autograft	Human keratinocytes	Keratinocytes dispersed in aerosol	Not reported	Nathoo et al. (2014)
Epidex	Autograft	Scalp hair follicles	Cultured keratinocytes on a silicon membrane	Not reported	Dai et al. (2020)
Epifix	Allograft	Human amion and chorion membrane	Basement membrane that contains epithelial cells	Collagen I, collagen III, decorin	Dai et al. (2020)
Alloderm	Allograft	Human cadaveric skin	Decellularized cryopreserved basement membrane	Collagen I, elastin	Nathoo et al. (2014)
dCELL	Allograft	Human cadaveric dermis	Decellularized dermis cryopreserved with glycerol	Collagen I, collagen III, decorin	Elliott et al. (2015)
TransCyte	Allograft	Human newborn fibroblasts	Bilayer graft: 1) nylon mesh coated with porcine dermal collagen, and 2) silicon membrane seeded with fibroblasts	Collagen I, collagen III, collagen V, fibronectin, versican, decorin, tenascin	Noordenbos et al. (1999)
Dermagraft	Allograft	Human living neonatal foreskin fibroblasts	Cultured fibroblasts on a mesh made of polyglycolic acid	Collagen I, collagen III, collagen IV, elastin, decorin	Dai et al. (2020)
StrataGraft	Allograft	Neonatal keratinocytes	Neonatal keratinocytes used to produce a biologically functional stratified epidermis	Collagen I	Schurr et al. (2009)
Apligraft	Allograft	Bovine collagen and neonatal fibroblasts and keratinocytes	Layer of 1) collagen gel with neonatal fibroblast (dermis), and 2) neonatal keratinocytes (epidermis)	Collagen I	Trent and Kirsner, (1998)
OrCel	Allograft	Human neonatal foreskin fibroblasts and keratinocytes	Neonatal foreskin fibroblasts and keratinocytes cultured in bovine collagen sponge	Collagen I	Windsor et al. (2009)
Matriderm	Xenograft	Ligamentum nuchae of cattle	Lyophilized dermis coated with elastin hydrolysate	Collagen I, collagen III, collagen V, elastin	Halim et al. (2010)
Biobrane	Xenograft	Porcine collagen	Bilaminar nylon mesh filled with 1) collagen I, and 2) thin silicone lamina	Collagen I	Alrubaiy and Al-Rubaiy, (2009)
OASIS	Xenograft	Porcine jejunum submucosa	Lyophilized small intestine submucosa	Collagen I, Collagen III, Collagen IV, Collagen VI, fibronectin, elastin, hyaluronan, chondroitin sulfate, decorin	Yeh et al. (2017)
Integra	Xenograft	Bovine collagen and shark chondroitin sulfate	Layer of 1) collagen I from tendon, 2) chondroitine-6-sulfate, and 3) a silicone pseudoepidermis	Collagen I, chondroitin sulfate	Philandrianos et al. (2012)
Nevelia	Xenograft	Bovine collagen	Three-dimensional porous matrix composed of 1) collagen and 2) a semi-permeable silicone membrane	Collagen I	Nicoletti et al. (2018)
Permacol	Xenograft	Porcine dermal tissue matrix	Collagen and elastin crosslinked by diisocyante	Collagen I	Hsu et al. (2009)
Pri-matrix	Xenograft	Fetal bovine dermis	Acellular dermal matrix	Collagen I, collagen III	Sutjarittangtham et al. (2014)