Study	Reason for exclusion
Aaronson 1996	Patients with allergic rhinitis and concomitant symptomatic mild to moderate perennial asthma.
Berkowitz 2002	RCT on 488 children aged > 12 years and adults using fexofenadine/pseudoephedrine vs placebo. Data on children only could not be extracted and author did not respond to correspondence.
Berkowitz 2004	RCT on 298 children aged > 12 years and adults using single dose of fexofenadine/pseudoephedrine vs placebo. Data on children only could not be extracted and author did not respond to correspondence.
Bone 1996	Non RCT on allergic rhinitis with cough as an outcome. Spanish article translated.
Chiang 2006	RCT on an anti‐histamine but cough not reported as a symptom
Ciprandi 2001	RCT on 20 children with perennial rhino conjunctivitis or asthma or both. Authors contacted for clarification but no reply received.
Clemens 1997	Randomised, double‐blind, placebo‐controlled trial of antihistamine‐decongestant combination for acute respiratory infection.
Conde 1995	Comparison of Azelastine nasal spray (0.14 mg in each nostril twice a day) versus Ebastine tablets (10 mg). No placebo.
De Blic 2005	RCT using levocetirizine 5 mg once‐daily in reducing seasonal allergic rhinitis (SAR) symptoms. Cough was not an outcome measure.
Grimfeld 2004	Study to evaluate the efficacy and long‐term safety of loratadine in reducing the number of respiratory infections in children at 24 months, that is, not for treatment of cough.
Herman 1997	RCT in 125 children comparing azelastine nasal spray 0.14 mg/nostril twice daily (0.56 mg/day) and placebo nasal spray. Cough was not an outcome measure.
Homnick 2007	RCT in patients with cystic fibrosis, that is, does not fulfil criteria for non‐specific cough
Jaffe 1983	RCT comparing in 217 children 'Pholcolix' and 'Actifed' Compound, in children with acute cough.
Kaiser 1998	RCT designed to compare the efficacy and safety of Claritin‐D 24 Hour (once daily) with that of Claritin‐D 12 Hour (twice daily) and placebo in the treatment of patients with seasonal allergic rhinitis. Cough was not an outcome.
Kim 2006	RCT examining the effect of desloratadine in reducing the symptoms of perennial allergic rhinitis. Cough was not an outcome measure.
Mizoguchi 2007	Study on acute cold symptoms which included cough lasting 1 to 5 days
Mosges 1995	RCT comparing 2 antihistamines nasal sprays (Levocabastine and azelastine). No placebo group.
Paul 2004	RCT in 100 children with upper respiratory infections comparing dextromethorphan and diphenhydramine to placebo. Acute cough.
Prenner 2006	Multicenter RCT to assess the general and cardiac safety of desloratadine syrup in children aged 6 months to less than 2 years. Cough was not an outcome measure.
Pujet 2002	RCT in adults using 5‐days of an antihistaminic antitussive syrup, oxomemazine, combining a small quantity of guaifenesin, with a centrally acting antitussive, clobutinol.
Reid 1989	Multicentre RCT that recruited children with recurrent cough and/or wheeze and with airway hyper‐reactivity i.e. children thus have asthma‐like disorder.
Shi 1996	RCT in 170 children with cough treated with Zhenkeling oral liquor or pectoral syrup. Zhenkeling is a Chinese herbal Rx with unknown anti‐histamine properties.
Simons 2003	RCT in children to document safety. No cough outcomes identified as efficacy. No reports of cough as an adverse event in either active or placebo arms.
Yoder 2006	RCT in children with acute cough.