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. 2022 Mar;32(3):558–568. doi: 10.1101/gr.275533.121

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© 2022 Joseph et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see https://genome.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 4. — CoPTR values strongly correlate with observed growth rates. (A,B) log₂(PTR) estimates (y-axis) versus observed growth rates (x-axis; Methods), for two well predicted MAGs: MAG 6, classified as Flavobacteriales (A), and MAG 13, classified as SAR86 (B). Lines are linear regressions. (C) Comparison of per-MAG Pearson r (y-axis) for all MAGs with more than three pairs of measured growth rates and calculated PTRs. CoPTR values are compared to GRiD, DEMIC, and iRep. Significance was computed using a two-sided Mann–Whitney U test.