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. Author manuscript; available in PMC: 2022 Mar 4.
Published in final edited form as: Lancet Healthy Longev. 2022 Feb 7;3(2):e109–e118. doi: 10.1016/S2666-7568(22)00001-0

Table 1:

Baseline characteristics of study participants overall and by testosterone quartile

Overall Quartile 1 Quartile 2 Quartile 3 Quartile 4
Number of participants 5535 (100·0%) 1641 (29·6%) 1104 (20·0%) 1497 (27·0%) 1293 (23·4%)

Age, years 74·0 (71·7–77·7) 73·9 (71·6–77·4) 73·9 (71·7–77·8) 73·7 (71·5–77·2) 74·5 (72·0–78·1)

Age distribution, years
 70–74 2781 (50·2%) 847 (51·6%) 557 (50·5%) 792 (52·9%) 585 (45·2%)
 75–79 1745 (31·5%) 501 (30·5%) 351 (31·8%) 442 (29·5%) 451 (34·9%)
 80–84 760 (13·7%) 220 (13·4%) 143 (13·0%) 205 (13·7%) 192 (14·8%)
 ≥85 249 (4·5%) 73 (4·4%) 53 (4·8%) 58 (3·9%) 65 (5·0%)

Weight, kg* 69·8 (61·9–79·2) 69·0 (61·8–79·0) 69·6 (62·0–79·0) 70·4 (61·6–79·6) 69·8 (62·2–79·3)

Height, cm 159·0 (155·0–163·0) 159·0 (155·0–163·0) 159·0 (155·0–164·0) 160·0 (155·0–163·0) 159·0 (155·0–163·0)

Body-mass index, kg/m2
 <18·5 44 (0·8%) 15 (0·9%) 9 (0·8%) 11 (0·7%) 9 (0·7%)
 18·5–24·9 1560 (28·2%) 479 (29·2%) 296 (26·8%) 429 (28·7%) 356 (27·5%)
 25·0–29·9 2187 (39·5%) 635 (38·7%) 461 (41·8%) 575 (38·4%) 516 (40·0%)
 ≥30·0 1715 (31·0%) 504 (30·7%) 332 (30·1%) 477 (31·9%) 402 (31·1%)

Ethnicity
 European ancestry 5470 (98·8%) 1624 (99·0%) 1091 (98·8%) 1475 (98·5%) 1280 (99·0%)
 Other§ 65 (1·2%) 17 (1·0%) 13 (1·2%) 22 (1·5%) 13 (1·0%)

Blood pressure, mm Hg
 Systolic 137·0 (126·0–149·0) 136·0 (126·0–149·0) 138·0 (127·0–150·0) 138·0 (127·0–150·0) 137·0 (127·0–149·0)
 Diastolic 76·0 (70·0–83·0) 75·0 (69·0–82·0) 76·0 (70·0–84·0) 77·0 (70·0–84·0) 76·0 (70·0–84·0)

Smoking status
 Current 156 (2·8%) 33 (2·0%) 35 (3·2%) 43 (2·9%) 45 (3·5%)
 Former 1739 (31·4%) 524 (31·9%) 353 (32·0%) 470 (31·4%) 392 (30·3%)
 Never 3640 (65·8%) 1084 (66·1%) 716 (64·9%) 984 (65·7%) 856 (66·2%)

Alcohol consumption
 Current 4130 (74·6%) 1254 (76·4%) 830 (75·2%) 1116 (74·5%) 930 (71·9%)
 Former 216 (3·9%) 67 (4·1%) 38 (3·4%) 66 (4·4%) 45 (3·5%)
 Never 1189 (21·5%) 320 (19·5%) 236 (21·4%) 315 (21·0%) 318 (24·6%)

Cardiovascular disease risk factors
 Diabetes 440 (7·9%) 170 (10·4%) 82 (7·4%) 98 (6·5%) 90 (7·0%)
 Hypertension 4055 (73·3%) 1174 (71·5%) 816 (73·9%) 1108 (74·0%) 957 (74·0%)
 Dyslipidaemia 4268 (77·1%) 1266 (77·1%) 849 (76·9%) 1151 (76·9%) 1002 (77·5%)
 Impaired renal function 1007 (18·8%) 311 (19·0%) 190 (17·2%) 245 (16·4%) 261 (20·2%)

Data are n (%) or median (IQR).

*

Data available for 5517 participants.

Data available for 5521 participants.

Data available for 5506 participants.

§

Other includes 32 Asian participants and seven Aboriginal or Torres Strait Islander participants.

Data available for 5382 participants.