REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Anti-p300	Aabcam	Cat#ab14984; RRID: AB_301550
Anti-Brg-1	Santa Cruz Biotechnology	Cat#sc17796; RRID: AB_626762
Anti-Gcn5	Santa Cruz Biotechnology	Cat#sc365321x; RRID: AB_10846182
Anti-RBBP5	Bethyl Laboratories	Cat#A300-109A; RRID: AB_210551
Anti-TBL1XR1	Santa Cruz Biotechnology	Cat#sc100908; RRID: AB_1130006
Anti-HDAC1	Abcam	Cat#ab7028; RRID: AB_305705
Anti-MED1	Bethyl Laboratories	Cat#A300-793A; RRID: AB_577241
Anti-BRD4	Bethyl Laboratories	Cat#A301-985A50; RRID: AB_1576498
Anti-NFkB p65	Santa Cruz Biotechnology	Cat#sc372; RRID: AB_632037
Anti-NFkB p65	Santa Cruz Biotechnology	Cat#sc8008; RRID: AB_628017
Anti-ICSBP	Santa Cruz Biotechnology	Cat#sc6058x; RRID: AB_649510
Anti-IRF3	Cell Signaling Technology	Cat#D83B9; RRID: AB_1904036
Anti-IRF2	Santa Cruz Biotechnology	Cat#sc374327; RRID: AB_10990717
Anti-PU.1	Santa Cruz Biotechnology	Cat#sc352; RRID: AB_632289
Donkey anti-Goat IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 488	ThermoFisher Scientific	Cat#A-11055; RRID: AB_2534102
Goat anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 488	ThermoFisher Scientific	Cat#A-11029; RRID: AB_138404
Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 488	ThermoFisher Scientific	Cat#A-11034; RRID: AB_2576217
Goat anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 647	ThermoFisher Scientific	Cat#A32728; RRID: AB_2633277
Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 647	ThermoFisher Scientific	Cat#A32733; RRID: AB_2633282
Goat anti-Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody, HRP	ThermoFisher Scientific	Cat#G-21234; RRID: AB_2536530
Goat anti-Mouse IgG (H+L) Cross-Adsorbed Secondary Antibody, HRP	ThermoFisher Scientific	Cat#G-21040; RRID: AB_2536527
Chemicals, peptides, and recombinant proteins
Lipopolysaccharides from Escherichia coli O111:B4	Sigma-Aldrich	Cat#L3024
Human IFN-gamma Recombinant Protein	ThermoFisher Scientific	Cat#PHC4031
Protease Inhibitor Cocktail	Sigma-Aldrich	Cat#P8340
Phosphatase Inhibitor Cocktail A	Santa Cruz Biotechnology	Cat#sc45055
Phorbol 12-myristate 13-acetate	Sigma-Aldrich	Cat#P8139
Deposited data
RBBP5 ChIP-seq data, performed in K562 cells	ENCODE	ENCFF666PCE
EP300 ChIP-seq data, performed in K562 cells	ENCODE	ENCFF755HCK
SMARCA4 ChIP-seq data, performed in K562 cells	ENCODE	ENCFF267OGF
TBL1XR1 ChIP-seq data, performed in K562 cells	ENCODE	ENCFF868SWL
CASCADE microarray data	GEO	GSE148945
Experimental models: Cell lines
THP-1	ATCC	Cat#TIB-202
Oligonucleotides
Protein Binding Microarray Double-stranding Primer	Eurofins	5′ - CAGCAGCGCTCAAGG AATCAAGAC - 3′
Software and algorithms
RColorBrewer, version 1.1.2	Neuwirth49	N/A
Cowplot, version 1.1.1	Wilke50	N/A
ggseqlogo R package, version 0.1	Wagih51	N/A
TOMTOM (MEME suit), version 5.0.3	Patwardhan et al.52	N/A
FASTQC, version 0.11.8	Kalita et al.53	N/A
Trim Galore, version 0.4.2	Goodwin et al.54	N/A
cutadapt, version 1.9.1	Bentley et al.55	N/A
bowtie2, version 2.3.4.1	Langmead and Salzberg56	N/A
samtools, version 1.8.0	Patwardhan et al.52	N/A
IMPUTE2, version 2.3.0	Verma et al.36	N/A
cnvPartition, version 3.2.1	Illumina Genome Studio	N/A
MARIO, version 3.9.3	Verma et al.36	N/A
UpSetR Package, version 1.4.0	Conway et al.57	N/A
CASCADE R-scripts, version 1.0.0	https://github.com/Siggers-Lab/CASCADE_paper	N/A
ggplot2, version 3.3.5	Wickham58	N/A