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Structure of influenza A virus virions. Two glycoprotein spikes, HA and NA, and the M2 protein are embedded in the lipid bilayer derived from the host plasma membrane. The RNP consists of a viral RNA segment associated with the NP and the three polymerase proteins (PA, PB1, and PB2). The M1 protein is associated with both RNP and the viral envelope, while NS2 is associated with RNP through interaction with M1. NS1 is the only nonstructural protein of influenza A virus.
