TABLE 3.
HA cleavage site sequence of avian influenza virus isolates
| Subtype | Isolate | Amino acid sequence a ←HA1 | | HA2→ |
|---|---|---|
| H5 | ||
| Avirulent | ||
| Most avirulent | P Q - - - - R E T R G L | |
| Recent avirulent in United States | P Q - - - - R K T R G L | |
| A/Chicken/Pennsylvania/1/83 (H5N2) | P Q - - - - K K K R G L | |
| Virulent | ||
| A/Chicken/Scotland/59 (H5N1) | P Q - - - - R K K R G L | |
| A/Tern/South Africa/61 (H5N3) | P Q R E T R R Q K R G L | |
| A/Turkey/Ontario/7732/66 (H5N9) | P Q - - (R) R R K K R G L | |
| A/Chicken/Pennsylvania/1370/83 (H5N2) | P Q - - - - K K K R G L | |
| A/Turkey/Ireland/1378/85 (H5N8) | P Q - - R K R K K R G L | |
| A/Turkey/England/50-92/91 (H5N1) | P Q - - R K R K T R G L | |
| A/Chicken/Queretaro-19/95 (H5N2) | P Q - - R K R K T R G L | |
| A/Chicken/Queretaro-20/95 (H5N2) | P Q R K R K R K T R G L | |
| A/Chicken/Hong Kong/258/97 (H5N1) | P Q R E R R R K K R G L | |
| A/Hong Kong/156/97 (H5N1) | P Q R E R R R K K R G L | |
| A/Chicken/Italy/1487/97 (H5N2) | P Q - - R R R K K R G L | |
| H7 | ||
| Avirulent | P E X P - - - - K X R G L | |
| Virulent | ||
| A/Chicken/Brescia/02 (H7N7) | P E P S - K K R K K R G L | |
| A/Fowl plague virus/Dutch/27 (H7N7) | P E P P - K K R R K R G L | |
| A/Fowl plague virus/Dobson/27 (H7N7) | P E L P - K K R R K R G L | |
| A/Fowl plague virus/Rostock/34 (H7N1) | P E P S - K K R K K R G L | |
| A/Fowl plague virus/Egypt/45 (H7N1) | F S - K K R R K R G L | |
| A/Turkey/England/63 (H7N3) | P E T P - - K R R R R G L | |
| A/Chicken/Victoria/76 (H7N7) | P E I P - K K R E K R G L | |
| A/Turkey/England/199/79 (H7N7) clone 1 | P E I P - K K R E K R G L | |
| A/Turkey/England/199/79 (H7N7) clone 2 | P E I P - - K K R K R G L | |
| A/Chicken/Leipzig/79 (H7N7) | P E I P - - K K K K R G L | |
| A/Goose/Leipzig/137-8/79 (H7N7) | P E I P - - K R K K R G L | |
| A/Goose/Leipzig/187-7/79 (H7N7) | P E I P K K K K K K R G L | |
| A/Goose/Leipzig/192-7/79 (H7N7) | P E I P - K K R K K R G L | |
| A/Chicken/Victoria/85 (H7N7) | P E I P - K K R E K R G L | |
| A/Chicken/Victoria/92 (H7N3) | P E I P - - K K K K R G L | |
| A/Chicken/Queensland/95 (H7N3) | P E I P - - R K R K R G L | |
| A/Chicken/Pakistan/1369/95 (H7N2) | P E I P - - K R R K R G L | |
| A/Chicken/Pakistan/447-4/95 (H7N3) | P E I P - K R K R K R G L |
a
Some clones have additional R (shown in parentheses).