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. 2022 Mar 4;17(3):e0264854. doi: 10.1371/journal.pone.0264854

Table 2. Echocardiographic and morphometric data.

Groups P values
SA0 (n = 14) SA2 (n = 13) SA5 (n = 14) IA0 (n = 12) IA2 (n = 12) IA5 (n = 12) P (I) P (A) P (IxA)
Food intake (g) 23±0.6 22.6±0.7 23.7±0.6 24.8±0.5 23.1±0.5 23.2±0.8 0.257 0.254 0.194
Initial BW (g) 266±9 260±9 275±8 252±5 260±8 258±7 0.133 0.605 0.595
Final BW (g) 430±10 432±14 436±11 452±11 445±13 447±13 0.127 0.949 0.906
Infarction size (%) - - - 42.8±1.9 39.7±2.7 42.1±1.8 - 0.556 -
*LVSD/BW (mm/kg) 9.52±0.43 9.39±0.29 8.81±0.33 17.5±0.98 17.6±1.09 18.5±0.84 <0.0011 0.994 0.297
*LVDD/BW (mm/kg) 18.4±0.3 18.8±0.5 17.8±0.5 22.7±0.8 22.9±1 23.3±0.8 <0.0011 0.901 0.428
*LVMI (g/kg) 1.7±0.04 1.8±0.07 1.7±0.07 3.3±0.21 3±0.2 3.2±0.22 <0.0011 0.921 0.217
#LA/BW (mm/kg) 12±0.3 13±0.4 12±0.3 16±1 15±1.1 15±0.9 0.0051 0.132 0.665
#FAC (%) 69±1.7 67±1.1 68±1.2 32±3 33±1.8 31±3.3 <0.0051 0.538 0.605
*Ejection fraction 86±1.3 87±1.2 88±0.7 54±3.8 55±3.5 50±3.2 <0.0011 0.794 0.338
E’ media (cm/s) 3.9±0.2 4.1±0.2 4.1±0.1 3.9±0.2 3.6±0.2 3.6±0.1 0.0121 0.988 0.176
*A’ media (mm2) 3.7±0.2 3.5±0.2 3.3±0.2 2.9±0.2 2.9±0.3 3.5±0.4 0.0131 0.583 0.100
CSA (μm2) 207±34 252±27 245±25 304±28 275±30 289±28 0.0271 0.923 0.422

I: infarction; S: sham; A: açai; A0: no supplementation; A2: 2% açai supplementation; A5: 5% açai supplementation; BW: body weight; LVSD: left ventricular systolic diameter; LVDD: left ventricular diastolic diameter; LVMI: left ventricular mass index; LA: left atrium; FAC: fractional area change; E’ media: average between early diastolic wave of the mitral annulus lateral and septal; A’ media: average between late diastolic wave of the mitral annulus lateral and septal; CSA: cardiomyocyte cross-sectional area. Data are expressed as mean ± SEM. Bold numbers represents significant effects considered.

1 Comparisons for I factor: infarcted animals different from sham animals.

* variables normalized for 2-factor ANOVA test.

# Mann Whitney and Kruskal Wallis.