Table 2. Echocardiographic and morphometric data.
Groups | P values | ||||||||
---|---|---|---|---|---|---|---|---|---|
SA0 (n = 14) | SA2 (n = 13) | SA5 (n = 14) | IA0 (n = 12) | IA2 (n = 12) | IA5 (n = 12) | P (I) | P (A) | P (IxA) | |
Food intake (g) | 23±0.6 | 22.6±0.7 | 23.7±0.6 | 24.8±0.5 | 23.1±0.5 | 23.2±0.8 | 0.257 | 0.254 | 0.194 |
Initial BW (g) | 266±9 | 260±9 | 275±8 | 252±5 | 260±8 | 258±7 | 0.133 | 0.605 | 0.595 |
Final BW (g) | 430±10 | 432±14 | 436±11 | 452±11 | 445±13 | 447±13 | 0.127 | 0.949 | 0.906 |
Infarction size (%) | - | - | - | 42.8±1.9 | 39.7±2.7 | 42.1±1.8 | - | 0.556 | - |
*LVSD/BW (mm/kg) | 9.52±0.43 | 9.39±0.29 | 8.81±0.33 | 17.5±0.98 | 17.6±1.09 | 18.5±0.84 | <0.0011 | 0.994 | 0.297 |
*LVDD/BW (mm/kg) | 18.4±0.3 | 18.8±0.5 | 17.8±0.5 | 22.7±0.8 | 22.9±1 | 23.3±0.8 | <0.0011 | 0.901 | 0.428 |
*LVMI (g/kg) | 1.7±0.04 | 1.8±0.07 | 1.7±0.07 | 3.3±0.21 | 3±0.2 | 3.2±0.22 | <0.0011 | 0.921 | 0.217 |
#LA/BW (mm/kg) | 12±0.3 | 13±0.4 | 12±0.3 | 16±1 | 15±1.1 | 15±0.9 | 0.0051 | 0.132 | 0.665 |
#FAC (%) | 69±1.7 | 67±1.1 | 68±1.2 | 32±3 | 33±1.8 | 31±3.3 | <0.0051 | 0.538 | 0.605 |
*Ejection fraction | 86±1.3 | 87±1.2 | 88±0.7 | 54±3.8 | 55±3.5 | 50±3.2 | <0.0011 | 0.794 | 0.338 |
E’ media (cm/s) | 3.9±0.2 | 4.1±0.2 | 4.1±0.1 | 3.9±0.2 | 3.6±0.2 | 3.6±0.1 | 0.0121 | 0.988 | 0.176 |
*A’ media (mm2) | 3.7±0.2 | 3.5±0.2 | 3.3±0.2 | 2.9±0.2 | 2.9±0.3 | 3.5±0.4 | 0.0131 | 0.583 | 0.100 |
CSA (μm2) | 207±34 | 252±27 | 245±25 | 304±28 | 275±30 | 289±28 | 0.0271 | 0.923 | 0.422 |
I: infarction; S: sham; A: açai; A0: no supplementation; A2: 2% açai supplementation; A5: 5% açai supplementation; BW: body weight; LVSD: left ventricular systolic diameter; LVDD: left ventricular diastolic diameter; LVMI: left ventricular mass index; LA: left atrium; FAC: fractional area change; E’ media: average between early diastolic wave of the mitral annulus lateral and septal; A’ media: average between late diastolic wave of the mitral annulus lateral and septal; CSA: cardiomyocyte cross-sectional area. Data are expressed as mean ± SEM. Bold numbers represents significant effects considered.
1 Comparisons for I factor: infarcted animals different from sham animals.
* variables normalized for 2-factor ANOVA test.
# Mann Whitney and Kruskal Wallis.