Table 4. Oxidative stress markers.
Groups | P values | ||||||||
---|---|---|---|---|---|---|---|---|---|
SA0 (n = 8) | SA2 (n = 8) | SA5 (n = 8) | IA0 (n = 8) | IA2 (n = 8) | IA5 (n = 8) | P (I) | P (A) | P (IxA) | |
*LH (nmol/mg) | 250±10.9 | 241±13.5 | 251±11.9 | 301±15 | 286±15.2 | 254±15.4 | 0.0041 | 0.251 | 0.169 |
MDA (μmol/g) | 0.35±0.05a | 0.36±0.03b | 0.31±0.04 | 1.32±0.25a,A,C | 0.77±0.12b,A | 0.61±0.12C | <0.001 | 0.013 | 0.0233 |
CAT (μmol/mg) | 64.5±4.23 | 59.1±5.11 | 56.6±4.04 | 47.8±3.17 | 61±3.62 | 60.5±7 | 0.351 | 0.709 | 0.065 |
SOD (nmol/mg) | 7.06±0.36a | 7.34±0.36b | 7.59±0.31 | 8.95±0.38a,C | 8.74±0.54b,B | 6.9±0.41B,C | 0.011 | 0.095 | 0.0063 |
GPx (nmol/mg) | 45.0±3.1 | 43.9±1.87 | 45.6±1.82 | 34.6±1.44 | 39.9±2.31 | 43.6±2.92 | 0.0061 | 0.133 | 0.179 |
(n) Espression Nrf-2 | (8) 1.45±0.31 | (8) 1.48±0.39 | (7) 1.21±0.38 | (6) 1.05±0.34 | (8) 0.66±0.18 | (8) 0.75±0.16 | 0.0291 | 0.674 | 0.760 |
I: infarction; S: sham; A: açai; A0: no supplementation; A2: 2% açai supplementation; A5: 5% açai supplementation. LH: lipid hydroperoxide; MDA: malondialdehyde; CAT: catalase; SOD: superoxide dismutase; GPx: glutathione peroxidase; Nrf-2: expression of nuclear factor erythroid-2. Data are expressed as mean ± SEM. Bold numbers represents significant effects considered.
1 Comparisons for I factor: infarcted animals different from sham animals.
3 IxA: when interactions are observed, same superscript letters represents differences (P<0.05).
*variables normalized for 2-factor ANOVA test.