Table 5. Production of cytokines inflammatory.
Groups | P values | ||||||||
---|---|---|---|---|---|---|---|---|---|
SA0 | SA2 | SA5 | IA0 | IA2 | IA5 | P (I) | P (A) | P (IxA) | |
(n) IL-10 (pg/mg) | (6) 3.21±0.47a,E | (6) 4.81±0.71D | (6) 8.49±1.c,D,E | (6) 6.83±0.44a,A,C | (6) 4.75±0.62A,B | (6) 2.48±0.27c,B,C | 0.123 | 0.529 | <0.0013 |
INF-γ (pg/mg) | (6) 0.48±0.19 | (5) 1.05±0.32 | (5) 1.33±0.22 | (6) 0.48±0.18 | (6) 0.62±0.27 | (4) 0.13±0.08 | 0.0081 | 0.276 | 0.054 |
#TNF-α (pg/mg) | (6) 0.10±0.01 | (6) 0.02±0.02 | (6) 0.78±0.47 | (6) 0.24±0.16 | (6) 0.92±0.49 | (6) 0.53±00.33 | 0.699 | 0.250 | 0.427 |
Expression p NF-κB | (8) 0.85±0.10 | (8) 1.24±0.14 | (6) 1.08±0.21 | (6) 1.25±0.21 | (6) 1.03±0.27 | (7) 1.06±0.16 | 0.696 | 0.872 | 0.222 |
Expression NF-κB | (8) 0.94±0.16 | (8) 1.16±0.12 | (6) 1.09±0.25 | (6) 1.20±0.17 | (6) 0.96±0.20 | (7) 1.03±0.17 | 0.990 | 0.997 | 0.415 |
*Expression p NF-κB / NF-κB | (8) 1.00±0.10 | (8) 1.05±0.05 | (6) 0.97±0.13 | (6) 1.02±0.07 | (6) 0.86±0.06 | (7) 0.91±0.11 | 0.191 | 0.663 | 0.377 |
I: infarction; S: sham; A: açai; A0: no supplementation; A2: 2% açai supplementation; A5: 5% açai supplementation. IL-10: interleukin 10; INF-γ: interferon γ; TNF-α: tumor necrosis factor-α, NF-κB: nuclear factor kappa B. Data are expressed as mean ± SEM. Bold numbers represents significant effects considered.
1 Comparisons for I factor: infarcted animals different from sham animals.
3 IxA: when interactions are observed, same superscript letters represents differences (P<0.05).
*variables normalized for 2-factor ANOVA test.
#Mann Whitney and Kruskal Wallis.