Table 2. Meta-analysis of Studies Measuring Baseline Cytokine Levels in Responder and Non-responder.
Citochina | Responder (N) | Non Responder (N) | ES (IC 95%) | p-value | I2(%) |
IL-1β | 89 | 75 | 0.19 [−0.49, 0.86] | 0.64 | 74 |
IL-2 | 152 | 155 | 0.48 [−0.07, 1.03] | 0.09 | 81 |
IL-4 | 114 | 132 | –0.14 [−0.48, 0.20] | 0.41 | 38 |
IL-6 | 374 | 362 | 0.02 [−0.13, 0.17] | 0.79 | 1 |
IL-8 | 151 | 144 | –0.27 [−0.49, −0.05] | 0.02 | 10 |
IL-10 | 134 | 152 | –0.00 [−0.24, 0.23] | 0.98 | 29 |
TNFα | 380 | 282 | –0.03 [−0.33, 0.27] | 0.83 | 66 |
INFγ | 110 | 136 | –0.06 [−0.31, 0.19] | 0.64 | 45 |
PCR | 698 | 795 | –0.18 [−0.28, –0.08] | 0.0006 | 0 |
GM-CSF | 123 | 137 | 0.09 [−0.16, 0.33] | 0.48 | 0 |