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. 2022 Feb 25;52(1):36–52.

Table 2. Meta-analysis of Studies Measuring Baseline Cytokine Levels in Responder and Non-responder.

Citochina Responder (N) Non Responder (N) ES (IC 95%) p-value I2(%)
IL-1β 89 75 0.19 [−0.49, 0.86] 0.64 74
IL-2 152 155 0.48 [−0.07, 1.03] 0.09 81
IL-4 114 132 –0.14 [−0.48, 0.20] 0.41 38
IL-6 374 362 0.02 [−0.13, 0.17] 0.79 1
IL-8 151 144 –0.27 [−0.49, −0.05] 0.02 10
IL-10 134 152 –0.00 [−0.24, 0.23] 0.98 29
TNFα 380 282 –0.03 [−0.33, 0.27] 0.83 66
INFγ 110 136 –0.06 [−0.31, 0.19] 0.64 45
PCR 698 795 –0.18 [−0.28, –0.08] 0.0006 0
GM-CSF 123 137 0.09 [−0.16, 0.33] 0.48 0