Table 2.

Mucocutaneous characteristics of arbovirus infections

	Zika	Chikungunya	Dengue
Incubation period, d	3–14	1–12	5–8
Cutaneous manifestations in symptomatic individuals	90% of infections, morbilliform or fine papular eruption, descends from trunk to lower extremities, can be pruritic	∼50% of infections, morbilliform, typically spares face, involves trunk and limbs, can be pruritic Chik sign: centrofacial hyperpigmentation	∼50% of infections, facial, trunk, extremities, white “islands in sea of red,” confluent erythema that can progress to morbilliform, typically not pruritic, usually spares palms and soles
Mucosal findings	Common, 55%, nonpurulent conjunctivitis	Uncommon	−15% to 30%, conjunctival or scleral injection, cracked lips, strawberry tongue, vesicles on soft palate
Laboratory findings	Nonspecific	Nonspecific	Thrombocytopenia