Figure 2.
Alpha and beta diversities of WT, PXR-null, CAR-null, and PXR-CAR-null mice. (A) Mean (SE) alpha diversity of gut microbiota within WT, PXR-null, CAR-null, and PXR-CAR-null mice. Line plots are generated using the R package ggplot. Asterisks (∗) represent statistically significant differences compared to WT mice (one-way ANOVA followed by Duncan's post hoc test, P < 0.05). (B) Principal components analysis (PCA) plots showing the beta diversities of adolescent male, adult male, adolescent female, and adult female WT, PXR-null, CAR-null, and PXR-CAR-null mice.