Figure 3.
In vitro anti-proliferation, pro-apoptotic, and anti-mobility properties of TFENs. (A) Viabilities of various cell lines with the treatment of TFENs for 24, 48, and 72 h, respectively, and (B) their corresponding IC50 values. Each point represents the mean ± SEM (n = 5). (C) Pro-apoptotic capacities of TFENs against MCF-7 cells and 4T1 cells after co-incubation for 4 and 8 h, respectively. (D, F) Migration and (E, G) invasion of MCF-7 cells and 4T1 cells with or without the treatment of TFENs for 24 h, and their corresponding quantitative results. Scale bar = 100 μm. Each point represents the mean ± SEM (n = 3). ∗P < 0.05, ∗∗P < 0.01. ns, no significance. (H) The schematic illustration of the impacts of TFENs on healthy cells and cancer cells.