Fig. 6.

S11e promotes apoptosis of fibrosarcoma cells. (A) HT1080 and MRC-5 cells were incubated with the indicated 16 μM concentrations of S11e or randomized Library. After adding CCK-8, the cytotoxicity of 24 h, 48 h, and 72 h treatment was detected by microplate reader (Comparison, S11e vs Library: ***p < 0.001; ns, not significant). (B) Detection of apoptotic effects of aptamers on HT1080 cells and MRC-5 cells by flow cytometry. (C) Statistical evaluation of apoptotic flow cytometry results (Comparison, S11e vs Library: *p < 0.05; **p < 0.01; ns, not significant).