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. 2021 Oct 21;12:153–168. doi: 10.1016/j.bioactmat.2021.10.013

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© 2021 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — Functions verification of MS@MCL in vitro. A) Comparison of the loading amount of LOX among different bonding forms. B) Comparison of the enzymatic activity between immobilized and free MCL under different pH conditions. C) Comparison of the heat stability between immobilized and free MCL. D) Comparison of the lactate consumption effect among MS@MnO₂, MS@MCL and MCL. E) Dissolved oxygen profiles of the mixed solution of MS@MCL and H₂O₂ at pH 7.4 and 5.5. F) Mn²⁺ release profiles of MS@MCL under different conditions. G) T1-weighted MRI of Mn²⁺ from MS@MCL under different conditions. H) The fitting curve of longitudinal relaxivity and Mn²⁺ concentration.