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. 2021 Oct 19;12:169–184. doi: 10.1016/j.bioactmat.2021.10.017

Fig. 7.

Fig. 7

In vivo application of the double-bonded hydrogel. A) The process of screw implantation in SD rats. B) Micro-CT 3D reconstructed images. C-E) Micro-CT analysis of BV/TV, Conn.D and Tb.N (n = 4, all values were mean ± std. dev., NS, not significant, *p < 0.05, **p < 0.01, ***p < 0.001 when comparing A-H + AB-O and other groups via two-way ANOVA analysis followed by Tukey's multiple comparison test by GraphPad Prism 7.0 Software (USA)). F) The results of pull-out testing (n = 3, all values were mean ± std. dev., NS, not significant, *p < 0.05, **p < 0.01, ***p < 0.001 when comparing A-H + AB-O and other groups via two-way ANOVA analysis followed by Tukey's multiple comparison test by GraphPad Prism 7.0 Software (USA)). G) Histomorphometric results of BIC (n = 4, all values were mean ± std. dev., NS, not significant, *p < 0.05, **p < 0.01, ***p < 0.001 when comparing A-H + AB-O and other groups via two-way ANOVA analysis followed by Tukey's multiple comparison test by GraphPad Prism 7.0 Software (USA)). H) Representative samples stained with toluidine.