H&E and Masson staining. A-B) H&E and Masson staining in each group, 4- and 8- weeks post-surgery. C-D) quantitative results of H&E and Masson staining in the proportion of bone collagen (n = 3, all values were mean ± std. dev., NS, not significant, *p < 0.05, **p < 0.01, ***p < 0.001 when comparing A-H + AB-O and other groups via two-way ANOVA analysis followed by Tukey's multiple comparison test by GraphPad Prism 7.0 Software (USA)).