Figure 1.
XH30 inhibited cell proliferation in various brain tumor cell lines. (A) Chemical structure of XH30. (B) Kinase interaction maps of XH30. (C) Relative sensitivity of brain tumor cells to XH30. Cell inhibition was assessed by MTT assay after 72 h incubation with the indicated compounds. The IC50 values are presented as mean ± SD, n = 3. (D) The expression pattern of PI3K signaling pathway in various brain tumor cells. The cells were then lysed and examined on crucial proteins of PI3K pathway signaling by immunoblotting.