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. 2021 May 26;12(2):774–786. doi: 10.1016/j.apsb.2021.05.019

Figure 5.

Figure 5

XH30 repressed glioblastoma growth in subcutaneous xenograft models. (A) The tumor growth curve in U251 xenograft mice model. Data are presented as mean ± SD, n = 6. ANOVA analysis, ∗∗∗P < 0.001, compared to vehicle group. (B) The tumor weight in U251 xenograft mice model. ANOVA analysis, ∗∗P < 0.01, ∗∗∗P < 0.001, compared to vehicle group. Data are presented as mean ± SD, n = 6. (C) Histological analysis of tumor issues in U251 xenograft model. Ki67 and p-AKT (473) staining. Scale bar: 50 μm. (D) The tumor growth curve in U373 xenograft mice model. Data are presented as mean ± SD, n = 6. ANOVA analysis, ∗∗∗P < 0.001, compared to vehicle group. (E) The tumor weight in U373 xenograft mice model. Data are presented as mean ± SD, n = 6. ANOVA analysis, ∗∗∗P < 0.001, compared to vehicle group. (F) XH30 inhibited PI3K signaling pathway in tumor tissue from U373 xenograft mice model.