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. 2021 Aug 21;12(2):924–938. doi: 10.1016/j.apsb.2021.08.018

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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The combination of LPs-R848 with MM-LPs-POD exerted improved antitumor efficacy. (A) Schematic showing of the arrangements for animal experiments. (B) In vivo bioluminescence images to monitor the size of tumors in the different groups of mice that received various treatments and (C) the corresponding ROI analysis of tumors. (D) Photos and (E) weight of tumors at the end of the experiment, and (F) change in tumor growth (n=6). (G) Images of HE, Ki67 and TUNEL staining of tumor slices. Scale bar: 100 μm. Data are shown as the mean±SD and analyzed by unpaired two-tailed Student's t-test. ^∗∗∗P<0.001, ^∗∗∗∗P<0.0001. n.s., not significant.