. Author manuscript; available in PMC: 2023 May 1.

Published in final edited form as: Int J Cancer. 2022 Jan 13;150(9):1447–1454. doi: 10.1002/ijc.33897

Table 2.

HR and 95% CI for the association between SNP rs1933736 and CRC-specific mortality, stratified by sex

SNP	Gene	CA/RA	CAF	HR (95% CI)^a		P _interaction	Corrected P_interaction^b
SNP	Gene	CA/RA	CAF	Female	Male	P _interaction	Corrected P_interaction^b
rs1933736	FRK	C/T	0.42	1.11 (1.04, 1.19)	0.88 (0.82, 0.94)	8.00 × 10⁻⁷	0.0004

SNP = Single-Nucleotide Polymorphisms; CA = Coded Allele; RA = Reference Allele; CAF = Coded Allele Frequency; HR = Hazard Ratio; CI = Confidence Interval; CRC = Colorectal Cancer.

Adjusted for age at diagnosis categories, genotyping platform/study, and the first three principal components.

P values were adjusted using Bonferroni method using M_{eff_G}.