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. 2021 Dec 27;7(3):455–464. doi: 10.1016/j.ekir.2021.12.025

Table 4.

Changes in the lipid levels tween baseline and week 12 in the 2 roxadustat initial-dose groups

Variable Standard-dose group
Low-dose group
P for trend
Baseline Week 12 P Baseline Week 12 P
Triglyceride 1.6 (1.3–2.1) 1.3 (1.1–2.2) 0.03 1.7 (1.2–2.8) 1.7 (1.2–3.4) 0.95 0.04
Total cholesterol 4.1 ± 0.8 3.6 ± 0.9 0.01 4.3 ± 1.0 4.0 ± 1.1 0.03 0.29
HDL 1.0 ± 0.3 0.9 ± 0.2 0.01 0.9 ± 0.3 0.8 ± 0.3 0.002 0.33
LDL 2.0 ± 0.5 2.0 ± 0.6 0.37 2.2 ± 0.7 2.0 ± 0.7 0.051 0.31

HDL, high density lipoprotein; LDL, low density lipoprotein.

P for trend compared the change trend between roxadustat initial-dose groups; p, compared between baseline and week 12.