TABLE 1.
Studies involving a detailed analysis of the aerobic and anaerobic microbiology of noninfected wounds without specifically investigating the role of microorganisms in wound healing
| Author (reference) | Study description (no. of wounds) | No. of microbial isolates (% that were anaerobes) | Predominant isolates |
|---|---|---|---|
| Louie et al. 1976 (143) | Microbiology of 20 diabetic ulcers (scrapings of ulcer bed and wound edge) | 116 (45) | Bacteroides spp., Peptostreptococcus spp., Proteus spp. |
| Brook et al. 1981 (46) | 392 specimens taken from burn sites in 180 children | 580 (23) | S. epidermidis, S. aureus, alpha-hemolytic streptococci, Propionibacterium acnes, Peptostreptococcus spp., Bacteroides spp. |
| Sapico et al. 1986 (213) | 49 specimens from 25 pressure sores | 130 (24) | Bacteroides spp., coliforms, P. aeruginosa |
| Brook 1987 (33) | Aspirates from human and animal bite wounds in 39 children | 59 from animal bites (37); 97 from human bites (55) | S. aureus, Peptostreptococcus spp., Bacteroides spp. (in both wound groups) |
| Brook et al. 1990 (42) | Analysis of 584 wounds from many sites | 1,470 (62) | Bacteroides spp., Peptostreptococcus spp., S. aureus, Clostridium spp., Fusobacterium spp. |
| Brook 1991 (37) | Analysis of decubitus ulcers in 58 children | 132 (40) | S. aureus, Peptostreptococcus spp., B. fragilis group, P. aeruginosa |
| Hansson et al. 1995 (98) | Analysis of leg ulcers without clinical signs of infection in 58 patients | 325 (22) | S. aureus, Enterococcus faecalis, Enterobacter cloacae, Peptostreptococcus magnus |
| Brook et al. 1998 (44) | 43 swab specimens from chronic leg ulcers in 41 patients | 97 (34) | S. aureus, Peptostreptococcus spp., B. fragilis group |
| Bowler et al. 1999 (28) | Swab specimens from 30 noninfected leg ulcers without clinical signs of infection | 110 (36) | S. aureus, coliforms, coagulase-negative staphylococci, fecal streptococci, Peptostreptococcus spp. |