TABLE 3.
Studies involving a detailed microbiological analysis of the aerobic and anaerobic microbiology of infected wounds
| Author (reference) | Study description and no. of wounds | No. of microbial isolates (% that were anaerobes) | Predominant isolates |
|---|---|---|---|
| Sanderson et al. 1979 (212) | Anaerobes in 65 purulent postappendectomy wounds (swab samples) | 179 (54) | E. coli, Bacteroides spp., Peptostreptococcus spp. |
| Brook et al. 1981 (46) | Analysis of 209 cutaneous abscesses in children | 467 (58) | S. aureus, Streptococcus spp., E. coli, Bacteroides spp. |
| Wheat 1986 (243) | Analysis of 131 infected diabetic foot ulcers in 130 patients | 538 (21) | Peptostreptococcus spp., Enterococcus spp., Staphylococcus spp. |
| Brook 1989 (34) | 89 specimens from postsurgical abdominal wound infections | 235 (55) | E. coli, Bacteroides spp., Peptostreptococcus spp., Clostridium spp. |
| Brook 1989 (36) | Specimens from 74 patients with postthoracotomy sternal wound infections | 87 (22) | S. epidermidis, S. aureus, coliforms, Peptostreptococcus spp. |
| Brook 1989 (35) | Analysis of pus from a Bartholin's abscess in 28 patients | 67 (64) | Bacteroides spp., Peptostreptococcus spp., E. coli |
| Brook et al. 1990 (42) | Analysis of 676 cutaneous abscesses | 1,702 (65) | Bacteroides spp., Peptostreptococcus spp., S. aureus, Clostridium spp., Fusobacterium spp. |
| Johnson et al. 1995 (116) | Swab samples from 43 diabetic foot ulcers (46 infected sites) | 285 (36) | Peptostreptococcus spp., Prevotella spp., Bacteroides spp. (emphasis on anaerobes) |
| Brook 1995 (38) | Analysis of pus from gastrostomy site wound infections in 22 children | 102 (44) | E. coli, Peptostreptococcus spp., Enterococcus spp., Bacteroides spp., S. aureus |
| Summanen et al. 1995 (226) | Comparison of the microbiology of soft tissue infections in IVDUa and non-IVDU (160 abscesses sampled) | 304 (43) from IVDU; 222 (48) from non-IVDU | S. aureus, “Streptococcus milleri,” Peptostreptococcus spp., Prevotella spp., Bacteroides spp., Streptococcus pyogenes |
| Brook 1996 (39) | Microbiology of specimens from 8 children with necrotizing fasciitis | 21 (62) | Peptostreptococcus spp., Streptococcus pyogenes, Bacteroides spp. |
| Di Rosa et al. 1996 (64) | Role of anaerobes in 300 postoperative wound infections | 639 (23) | Clostridium spp., Bacteroides spp., Peptostreptococcus spp. (emphasis on anaerobes) |
| Mousa 1997 (166) | Swab samples of burn wounds from 127 patients | 377 (31) | P. aeruginosa, S. aureus, Bacteroides spp., Peptostreptococcus spp., Klebsiella spp. |
| Brook et al. 1997 (43) | Analysis of perirectal abscesses in 44 patients | 456 (72) | B. fragilis group, Peptostreptococcus spp., Prevotella spp., S. aureus, Streptococcus spp. |
| Brook et al. 1998 (45) | Analysis of 368 specimens from 340 trauma patients with wound infection | 711 (63) | B. fragilis group, Peptostreptococcus spp., Clostridium spp., S. aureus, Prevotella spp. |
| Brook 1998 (40) | Analysis of 175 specimens from 166 children with infected traumatic wounds | 521 (70) | Peptostreptococcus spp., Prevotella spp. Fusobacterium spp., S. aureus, B. fragilis group |
| Pathare et al. 1998 (185) | Pus or tissue specimens from 252 diabetic foot infections | 775 isolates (29) | Staphylococcus spp., Streptococcus spp., Peptostreptococcus spp. |
| Bowler et al. 1999 (28) | Swab samples of 44 infected leg ulcers (based on clinical signs) | 220 isolates (49) | Peptostreptococcus spp., coliforms, coagulase-negative staphylococci, pigmented and nonpigmented gram-negative bacteria (anaerobes), fecal streptococci |
a
IVDU, intravenous drug user.