Figure 3.

Male-to-female cause-specific HRs and 95% CIs of the competing events KRT and death before KRT between subjects above or below 60 years of age at baseline, with/without CVD (i.e., congestive heart failure, peripheral vascular disorders or valvular disease), diabetes, and baseline eGFR <60 ml/min per 1.73 m²; models were adjusted for eGFR, eGFR slope, age, and all available comorbidities at baseline; continuous variables were incorporated via restricted cubic splines; P values denote interaction of sex and grouping variable. CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate; HR, hazard ratio; KRT, kidney replacement therapy.