All-cause mortality HR by eGFR at baseline, per comorbidity; adjusted for age, eGFR slope, and all other available comorbidities at baseline (see Table 1 for full list); continuous variables were incorporated via restricted cubic splines; left: diabetes yes/no, with interaction of diabetes diagnosis and eGFR; right: CVD yes/no (i.e., congestive heart failure, peripheral vascular disorders or valvular disease) with interaction of CVD diagnosis and eGFR. CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate; HR, hazard ratio; ref, reference.