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. 2022 Mar 4;13(3):206. doi: 10.1038/s41419-022-04632-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A, B The alternations in (A) ECAR and (B) OCR in PyMT and PyMT;Zeb1^cKO cells (n = 5). C The alternations in glucose uptake, pyruvate level, lactate production, and ATP level in PyMT and PyMT;Zeb1^cKO cells (n = 5). D, E The alternations in (D) ECAR and (E) OCR in Ctrl/231 and Zeb1/231 cells. F The alternations in glucose uptake, pyruvate level, lactate production, and ATP level in Ctrl/231 and Zeb1/231 cells. Dots depict individual samples in (A–C). Data are representative of five (A–C) or three (D–F) independent experiments and presented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 vs the respective control by an unpaired Student’s t-test.