Skip to main content
. 2022 Mar 4;13(3):207. doi: 10.1038/s41419-022-04612-3

Fig. 6. MiR-7682-3p mediated the antifibrotic effects of circRNA_37492.

Fig. 6

BUMPT cells were pre-transfected with either siRNA circRNA_37492 with miR-7682-3p inhibitor or siRNA circRNA_37492 only and co-treated with TGF-β1 for 24 h. A CircRNA_37492 expression by RT-qPCR analysis. B MiR-7682-3p expression by RT-qPCR analysis. C Type I, III collagen, FN and Fgb expression by western blot analysis. D Quantification of protein band of type I collagen, type III collagen, FN, and Fgb by grayscale analysis. Quantitative data are presented as the mean ± SD (n = 6 per group). *p < 0.05, TGF-β1 group vs. control group; #p < 0.05, siRNA circRNA_37492 with TGF-β1 group vs. TGF-β1 group; ^p < 0.05, siRNA circRNA_37492 plus with miR-7682-3p inhibitor and TGF-β1 group vs. siRNA circRNA_37492 with TGF-β1 group.