TABLE 2.
Participant measures by race
| African-American | White | P | |
|---|---|---|---|
| n (%) | 79 (49.7) | 80 (50.3) | |
| Age, Exam 1, M (SD) | 55.8 (6.8) | 55.7 (6.5) | .945 |
| Age, Exam 6, M (SD) | 71.5 (6.7) | 71.8 (6.6) | .810 |
| Sex (M/F) | 50/29 | 38/42 | .045* |
| Years of education, M (SD) | 14.9 (2.7) | 15.1 (2.8) | .729 |
| aCognitive status | .618 | ||
| Normal, n (%) | 49 (62.8) | 57 (72.2) | |
| MCI, n (%) | 24 (30.8) | 18 (22.8) | |
| Dementia, n (%) | 3 (3.9) | 3 (3.8) | |
| APOE-ε4, (+/−/missing) | 31/45/3 | 22/55/3 | .283 |
| % ASCVD, M (SD) | 8.76 (6.8) | 5.45 (4.5) | <.001* |
| b% FSRP, M (SD) | 2.33 (2.4) | 1.78 (1.8) | .096 |
| CAIDE, M (SD) | 7.25 (2.3) | 6.55 (2.2) | .051 |
| SBP, M (SD) | 133.0 (21.9) | 121.0 (17.4) | <.001* |
| DBP, M (SD) | 75.7 (9.2) | 71.9 (11.0) | .020* |
| cCASI Exam 5, M (SD) | 89.7 (6.2) | 94.6 (3.7) | <.001* |
| dCASI Exam 6, M (SD) | 90.6 (7.2) | 94.3 (4.8) | <.001* |
| eCASI change (5 to 6), M (SD) | 0.8 (6.8) | −0.4 (4.9) | .224 |
| PiB SUVR, M (SD) | 1.27 (0.28) | 1.39 (0.37) | .029* |
| Aβ+, n (%) | 25 (31.7) | 32 (40.0) | .272 |
| fWMH vol. (% ICV), median (IQR) | 0.21 (0.11, 0.55) | 0.23 (0.10, 0.55) | .979 |
| dCort. Thick., mm, M (SD) | 2.66 (0.13) | 2.69 (0.12) | .143 |
Abbreviations: Aβ, β-amyloid; ASCVD, atherosclerotic cardiovascular disease risk estimate from the pooled cohort equation; FSRP, Framingham stroke risk profile; CAIDE, cardiovascular risk factors, aging, and incidence of dementia risk score; SBP, systolic blood pressure; DBP, diastolic blood pressure; CASI, Cognitive Abilities Screening Instrument; PiB SUVR, Pittsburgh compound B Standardized Uptake Value Ratio; Cort. thick., Cortical thickness; WMH vol., white matter hyperintensity volume; ICV, intracranial volume.
Statistically significant at P < .05
White n = 78; African-American n = 76.
White n = 80; African-American n = 78.
White n = 80; African-American n = 76.
White n = 79; African-American n = 79.
White n = 79; African-American n = 76.
White n = 79; African-American n = 78.