TABLE 3.

VRF-Imaging associations

	t	P	Race interaction P
PiB SUVR (n = 159)
ASCVDa	0.37	.716	.606
FSRPb,d	2.48	.014*	.254
CAIDEc	2.89	.004*	.666
WMH Volume (n = 157)
ASCVDa	3.71	<.001*	.157
FSRPb,d	3.94	<.001*	.183
CAIDEc	3.44	<.001*	.945
Cort. Thick. (n = 158)
ASCVDa	−4.28	<.001*	.004*
FSRPb,d	−3.69	<.001*	.013*
CAIDEc	−2.47	.014*	.975

Note: all VRFs include age, sex, and systolic blood pressure. VRF components listed in Supplementary Table 1.

Abbreviations: VRF, vascular risk factor; ASCVD, atherosclerotic cardiovascular disease risk estimate from the pooled cohort equation; FSRP, Framingham stroke risk profile; CAIDE, cardiovascular risk factors, aging, and incidence of dementia risk score; PiB SUVR, Pittsburgh compound B Standardized Uptake Value Ratio; WMH, white matter hyperintensity; Cort. thick., cortical thickness.

^aAdjusted for education and APOE-ε4 carriage.

^bAdjusted for education, race, and APOE-ε4 carriage.

^cAdjusted for race.

^dOne outlier excluded.

^*Significant at P < .05.