Fig. 7.

Survival analysis and area under the curves of risk factors. A Area under the curves (AUC) of baseline factors in the prediction of COVID-19 mortality. The cutoff of IL-6 at 33 pg/mL (sensitivity: 79%, specificity: 81%) was optimized by the highest point of AUC based on the Cutoff Finder tool (https://molpathoheidelberg.shinyapps.io/CutoffFinder_v1/). B AUC values in the stepwise combination of four baseline factors. Kaplan-Meier curves are shown for severely-ill versus moderately-ill patients (C), patients aged < 65 versus ≥65 years (D), patients with baseline IL-6 ≥ 33 pg/mL versus patients with IL-6 < 33 pg/mL (E). F Mortality rate and survival time of patients with the combined conditions of severely-ill, age ≥ 65, and baseline IL-6 ≥ 33 pg/mL