Figure 4.

Changes in circulating LDN, total neutrophils, G-CSF, CRP, FGF-23, and leptin after bariatric surgery. (a) Percent LDN, (b) absolute number LDN, (c) Polymorphonuclear neutrophils counts in whole blood cells, and (d) Plasma levels of G-CSF, CRP, FGF-23, and leptin at baseline (Pre-op) and after 3 and 6 months post-bariatric surgery. Median, minimum, and maximum numbers are indicated in the box and whiskers plot and each dot represents an individual participant. Wilcoxon signed-rank tests were used to perform pairwise comparisons of the dependent variable distributions within patients before surgery and at months 3 and 6. Results were considered significant with a p-value≤0·05. LDN indicates low-density neutrophils; PBMC, peripheral blood mononuclear cells; MOP, morbidly obese patients; NWC, normal-weight controls; mo, months.