Table 5.
Differentially expressed genes related to detoxifying enzymes, reactive oxygen species production and scavenger proteins
| Gene symbol | p-value | FDR | FC |
|---|---|---|---|
| ALOX15 | 0.009404 | 0.178 | 28.50 |
| CYP4F12 | 0.003076 | 0.138 | 5.29 |
| SOD2 | 0.000020 | 0.010 | 4.89 |
| CYP4F3 | 0.000146 | 0.029 | 4.79 |
| CYP2F1 | 0.000616 | 0.061 | 4.68 |
| PTGS2 | 0.000050 | 0.017 | 4.52 |
| CYP26A1 | 0.010522 | 0.184 | 3.75 |
| GPX2 | 0.025164 | 0.198 | 3.56 |
| NCF4 | 0.000259 | 0.038 | 3.43 |
| ALOX5AP | 0.000415 | 0.048 | 2.85 |
| GPX3 | 0.029752 | 0.202 | 2.29 |
| SRXN1 | 0.021324 | 0.195 | 2.26 |
| NQO2 | 0.016323 | 0.192 | 2.18 |
| TXN | 0.028512 | 0.201 | 1.88 |
| NCF1 | 0.031472 | 0.205 | 1.78 |
| ALOX5 | 0.034505 | 0.209 | 1.70 |
| PRDX3 | 0.027021 | 0.201 | -1.68 |
| PRDX1 | 0.028868 | 0.201 | -1.69 |
| CYBB | 0.020038 | 0.195 | -1.72 |
| PTGS1 | 0.038928 | 0.213 | -1.74 |
| PRDX2 | 0.038368 | 0.213 | -1.74 |
| SOD1 | 0.023026 | 0.196 | -1.78 |
| ALOXE3 | 0.024143 | 0.198 | -1.90 |
| GLRX3 | 0.017831 | 0.193 | -1.90 |
| GCLC | 0.013239 | 0.187 | -1.98 |
| CYP4V2 | 0.020294 | 0.195 | -2.05 |
| CYP1B1 | 0.010201 | 0.183 | -2.09 |
| CYP2U1 | 0.020974 | 0.195 | -2.10 |
| TXNRD3 | 0.015726 | 0.191 | -2.34 |
| ALOX12B | 0.013590 | 0.187 | -2.59 |
| ALOX15B | 0.010129 | 0.182 | -3.01 |
FDR indicates false discovery rate; FC, fold change.