Figure 1.

Citrate synthase activity (A), mitochondrial content (B), citrate synthase activity/mitochondrial content (C), mRNA expression of TFAM (D), SIRT3 (E) and SOD (F) activity of mouse placental samples collected at E12.5, E14.5, E16.5 and E18.5 (from three to six litters per gestational age). Significance was indicated when P< 0.05. Significant differences between groups as detected by post hoc analysis are denoted by different letters where A is different from B which is different from C. A is not different from A or AB, while B is not different from B, AB or BC. Data are presented as mean ± s.e.m. (n = 10, five per sex).