Table 2.
Parameter | All |
Brazil |
France |
Germany |
US |
|||||
---|---|---|---|---|---|---|---|---|---|---|
Men | Women | Men | Women | Men | Women | Men | Women | Men | Women | |
Median follow-up time, yr | 2.7 [1.2–4.1] | 2.5 [1.1–4.1] | 1.5 [0.5–2.0] | 1.5 [0.7–2.0] | 4.0 [2.8–4.5] | 4.0 [3.0–4.7] | 2.7 [1.2–4.9] | 3.2 [1.6–5.7] | 1.3 [0.6–2.0] | 1.3 [0.7–2.0] |
Patients reaching KRT, n | 1093 | 621 | 50 | 53 | 408 | 210 | 491 | 222 | 167 | 155 |
% of cohort | 23 | 18 | 13 | 15 | 21 | 21 | 33 | 20 | 17 | 17 |
eGFRa at dialysis initiation | 10.2 [7.9–13.7] | 9.9 [7.1–13.3] | 12.0 [10.0–20.8] | 11.5 [9.0–16.7] | 9.2 [7.2–11.9] | 8.7 [6.6–11.8] | 10.7 [8.4–14.2] | 10.3 [7.3–14.8] | 10.9 [8.6–14.9] | 9.8 [7.1–13.0] |
<5 | 3 | 5 | 0 | 0 | 5 | 8 | 2 | 4 | 1 | 1 |
5–9.9 | 45 | 46 | 13 | 28 | 52 | 54 | 43 | 40 | 40 | 51 |
≥10 | 53 | 49 | 87 | 72 | 43 | 38 | 56 | 56 | 59 | 48 |
eGFRa at transplantationb | 12.0 [9.5–15.0] | 12.9 [10.1–16.1] | 11.5 [8.0–15.0] | – | 12.0 [9.5–14.0] | 12.9 [10.5–16.1] | 6.6 [4.8–12.2] | – | 16.0 [10.7–18.0] | 19.7 [6.9–33.5] |
<5 | 3 | 0 | 0 | – | 2 | 0 | 33 | – | 0 | 0 |
5–9.9 | 25 | 24 | 50 | – | 25 | 20 | 33 | – | 22 | 50 |
≥10 | 71 | 76 | 50 | – | 74 | 80 | 33 | – | 78 | 50 |
Median time when eGFR was measured before KRT initiation, d | 17 [50–5] | 21 [61–7] | 42 [104–14] | 63 [108–40] | 15 [36–4] | 19 [49–6] | 15 [42–6] | 15 [47–7] | 62 [109–15] | 48 [91–16] |
Modality of initial KRT | ||||||||||
Dialysis (PD or HD) | 93 | 93 | 92 | 89 | 87 | 87 | 99 | 100 | 93 | 92 |
HD | 86 | 84 | 91 | 81 | 86 | 84 | 88 | 88 | 79 | 79 |
PD | 14 | 16 | 9 | 19 | 14 | 16 | 12 | 12 | 21 | 21 |
Kidney transplant | 7 | 7 | 8 | 11 | 13 | 13 | 1 | 0 | 7 | 8 |
eGFR, estimated glomerular filtration rate; HD, hemodialysis; KRT, kidney replacement therapy; PD, peritoneal dialysis; US, United States.
The most recent eGFR within 6 mo of KRT initiation; value reported in median [interquartile range], frequency.
The number of patients who received a transplant was 10 in Brazil, 81 in France, 7 in Germany, and 27 in the US.