Table 2.

Diagnostic criteria and treatments for multisystem inflammatory syndrome in children and Kawasaki disease

Multisystem inflammatory syndrome in children	Kawasaki disease
Persistent fever with elevated inflammatory markers (CRP, neutrophils) and evidence of single or multi-organ dysfunction (cardiac, respiratory, renal, GI, or neurology) Exclusion of other microbial or infectious causes ± SARS-CoV-2 PCR Treatment: Supportive care, inotropic support, IVIG, aspirin, steroids, anakinra and infliximab	Fever lasting for 5 or more days AND 4 of the 5 below:  Bilateral conjunctival injection without exudate  Erythema or cracking of the lips or erythema of the oral cavity  Polymorphous exanthem  Changes of peripheral extremities (edema or erythema)  Acute non-purulent cervical lymphadenopathy Treatment: High-dose IVIG with aspirin

CRP C-reactive protein, GI gastrointestinal, IVIG intravenous immunoglobulins, PCR polymerase chain reaction